PSV Eindhoven is set to host Napoli at the Philips Stadion in Eindhoven, Netherlands, on Tuesday, October 21, 2025, with kick-off scheduled for 20:00 CEST. This UEFA Champions League group stage match is crucial for both teams, as PSV aims to build on their recent domestic success, while Napoli seeks to recover from a challenging start in the competition.
In terms of injuries, PSV faces several concerns. Key players such as Alassane Pléa, Ruben van Bommel, and Kiliann Sildillia are sidelined, which may impact the team’s attacking and defensive options. Wessel Kuhn is also a major doubt for the match. Napoli has received a boost with Scott McTominay returning to full training, but Rasmus Højlund remains unavailable due to a thigh injury and will not be part of the squad traveling to the Netherlands. Lorenzo Lucca is expected to lead the attack in Højlund’s absence, with Giuseppe Ambrosino as his deputy.
Tactically, PSV is anticipated to employ a high-pressing 4-3-3 formation, focusing on quick transitions and exploiting spaces left by Napoli’s defense. The midfield trio of Joey Veerman, Ismaël Saibari, and Guus Til will be pivotal in controlling the tempo and linking defense to attack. In attack, the pace and creativity of players like Cody Gakpo and Noni Madueke will be crucial in breaking down Napoli’s defensive lines. Napoli, under manager Luciano Spalletti, is likely to adopt a more structured 4-3-3 approach with a focus on possession and quick, incisive passing. The midfield partnership of Piotr Zieliński and Frank Anguissa will be key in dictating play, while the attacking trio of Hirving Lozano, Victor Osimhen, and Lorenzo Insigne will look to capitalize on any defensive lapses by PSV.
Leading up to the match, the press has highlighted PSV’s strong home form and attacking prowess, with particular emphasis on their dynamic forward line. Analysts have noted that PSV’s ability to press high and transition quickly could pose significant challenges for Napoli’s defense. For Napoli, media coverage has focused on the absence of Højlund and the importance of McTominay’s return to bolster the midfield. Observers have pointed out that Napoli’s success will depend on their ability to maintain possession and break down PSV’s high press.
Pre-match analysis suggests that PSV will look to dominate possession and apply constant pressure on Napoli’s defense. Analysts expect Napoli to focus on maintaining defensive solidity and exploiting counter-attacking opportunities. The match is anticipated to be closely contested, with both teams eager to secure vital points in the group stage.
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Watch and Download PSV vs Napoli full match replay and highlights, At Tuesday, October 21, 2025. The match played at Philips Stadion, in Champions League, UEFA.
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